Abstract
AB005. OP-5 A new approach in bariatric operations: bridged mini gastric bypass is rabbit model suitable for an experimental study?
Talar Vartanoğlu Aktokmakyan1, Osman Bilgin Gülçiçek1, Ali Solmaz1, Merve Tokoçin1, Nihat Buğdayci1, Onur Tokoçin4, Ayşegül Güneş3, Tuğçe Çay2, Atilla Çelik1, Fatih Çelebi1
1Department of General Surgery, SBÜ İstanbul Bağcilar Education and Research Hospital, Istanbul, Turkey;2SBÜ İstanbul Bağcilar Education and Research Hospital, Department of Pathology, Istanbul, Turkey;3SBÜ İstanbul Bağcilar Education and Research Hospital, Department of Biochemistry, Istanbul, Turkey;4İstanbul Kağithane State Hospital, Academic emergency Department, Istanbul, Turkey
Correspondence to: Talar Vartanoğlu Aktokmakyan. Department of General Surgery, SBÜ İstanbul Bağcilar Education and Research Hospital, Istanbul, Turkey. Email: talarim@gmail.com.
Background: Obesity is a global health epidemic with considerable co-morbidities. The increasing demand for bariatric surgery has led to the emergence of new techniques. We modified previously described mini gastric bypass (MGB) technique via leaving a bridge at the most cranial 2 cm of the fundus of human stomach to the follow-up and treatment of the remnant stomach and duodenum. We would like to entitle this new technique as Bridged MGB (Sumer’s technique) and aimed to apply on rabbits as an experimental study.
Methods: The study was performed in the experimental animal laboratory of university after ethical approval was taken from the local ethic committee. Described new technique was applied to 2.1 and 3.2 kg two New Zealand rabbits.
Results: As a result of the operations, one of the rabbits died on the day of the operation; the other rabbit was ex postoperatively third day. In autopsies, although no problem was detected at the anastomoses; necrosis was detected in the large curvature of both rabbits.
Conclusions: Rabbit one of the popular experimental animals, has been shown to be different from the human gastrointestinal system in both arterial and topographic aspects and it has been emphasized that it varies according to the species and even the diet and the climate. We believe that our study failed as a result of these differences and that animals more similar to humans should be used in gastrointestinal experimental studies.
Keywords: Experimental study; mini gastric bypass (MGB); rabbit
Provenance and Peer Review: This abstract is included in “Abstracts from the 3rd Turkish National Congress on Bariatric and Metabolic Surgery, 21st-24th November 2019, Antalya-Turkey”, which is commissioned by the Guest Editor (Mehmet Mahir Özmen) for the series “Bariatric and Metabolic Surgery” published in Annals of Laparoscopic and Endoscopic Surgery. This abstract did not undergo external peer review.
Conflicts of Interest: The authors have completed the ICMJE uniform disclosure form (available at http://dx.doi.org/10.21037/ales-2019-bms-16). The series “Bariatric and Metabolic Surgery” was commissioned by the editorial office without any funding or sponsorship. The authors have no other conflicts of interest to declare.
Ethical Statement: The authors are accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved.
doi: 10.21037/ales-2019-bms-16
Cite this abstract as: Aktokmakyan TV, Gülçiçek OB, Solmaz A, Tokoçin M, Buğdayci N, Tokoçin O, Güneş A, Çay T, Çelik A, Çelebi F. OP-5 A new approach in bariatric operations: bridged mini gastric bypass is rabbit model suitable for an experimental study? Ann Laparosc Endosc Surg 2020;5:AB005.
