The 2017 Digestive Disease Institute Week (DDI Week) organized by the Cleveland Clinic was held successfully in Boca Raton, Florida, from Feb 14th to 18th. As a grand feast in the field of digestive disease, the symposium attracted numerous experts from all over the world to get together to have deep discussion on hot topics in the digestive field, including transanal endoscopic surgery (TES), transanal total mesorectal excision (TaTME), fecal incontinence and rectal prolapse, revisional bariatric/metabolic interventions (RBMI), etc.