The 2017 Digestive Disease Institute Week (DDI Week) organized by the Cleveland Clinic was held successfully in Boca Raton, Florida, from Feb 14th to 18th. As a grand feast in the field of digestive disease, the symposium gathered numerous experts from all over the world to have deeper discussions on hot topics in the digestive field, including transanal endoscopic surgery (TES), transanal total mesorectal excision (TaTME), fecal incontinence and rectal prolapse, revisional bariatric/metabolic interventions (RBMI), etc.